Target intelligence / Profile preview

Respiratory Syncytial Virus Nucleocapsid Protein N (N protein)

Target: N protein
Molecular classification: Structural protein, Viral protein

Overview

The nucleocapsid protein (N) of respiratory syncytial virus (RSV) is a structural protein that encapsidates the viral RNA genome, forming a left-handed helical nucleocapsid. This structure protects the viral RNA from degradation and serves as the template for mRNA synthesis and genome replication. The N protein binds tightly to the viral RNA and interacts with other viral proteins (P, L, M) for proper virion assembly and function. It is essential for viral replication and infectivity.

Biological functions

Genome encapsidationRNA bindingTranscription templateReplication templateViral assembly

Disease associations

InfectionRespiratory Syncytial Virus infection

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