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Target intelligence / Profile preview
Ret finger protein-like 4A (RFPL4A)
- Target
- RFPL4A
- Molecular classification
- Other (E3 ubiquitin protein ligase)
01
Overview
Ret finger protein-like 4A (RFPL4A) is a protein-coding gene in humans located on chromosome 19 and predicted to encode an E3 ubiquitin protein ligase. It is thought to participate in protein ubiquitination, potentially influencing autophagy, NF-kappaB signaling, innate immune response, and regulation of gene expression. The protein may be active in the cytosol and nucleus of cells, particularly in female germ cells. No evidence was found supporting its status as a typical therapeutic target or biomarker in current literature[1][3][4][6].
- Other names
- RFPL4ARFPL4RNF210ret finger protein like 4ARING finger protein 210
02
Biological functions
Protein homodimerizationProtein kinase bindingUbiquitin protein ligase activityPositive regulation of autophagyPositive regulation of NF-kappaB signal transductionRegulation of viral entry into host cellInnate immune responseRegulation of gene expression
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