Retinol saturase pseudogene

Retinol saturase pseudogene (ENSG00000246575) is classified as a pseudogene, meaning it is a segment of DNA that resembles a gene but is nonfunctional and does not encode a functional protein. It is related to, but distinct from, the functional retinol saturase gene (RETSAT), which plays a role in retinol (vitamin A) metabolism. As a pseudogene, ENSG00000246575 does not have known biological function, therapeutic relevance, or known interactions with drugs[7][2]. Key points: - Pseudogenes are generally considered nonfunctional with respect to protein coding, though some may have regulatory RNA roles; however, there is no evidence for such a role here[2][7]. - This gene is not a therapeutic or pharmacological target and is not involved in known disease mechanisms, biomarker roles, or drug interactions[7]. - ENSG00000246575 should not be confused with the functionally active retinol saturase gene, which in humans is RETSAT (Ensembl: ENSG00000042445)[3][7]. - The term “pseudogene” indicates likely loss of coding potential due to mutations such as frameshifts, premature stop codons, or loss of regulatory elements[2]. Interpretation: - Retinol saturase pseudogene (ENSG00000246575) is not a true target and is incorrect if queried as a pharmacologically relevant molecule or receptor[7]. - If you require information on the functional enzyme involved in retinol metabolism, refer instead to Retinol saturase (RETSAT)[3].

Other names

Retinol saturase (all-trans-retinol 13,14-reductase) pseudogeneRESAT pseudogene