Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
The retrievable inferior vena cava (IVC) filter is a medical device implanted into the IVC, a large abdominal vein, to capture blood clots and prevent pulmonary embolism (PE) in patients at high risk for venous thromboembolism (VTE) who cannot use anticoagulation.[1][3][4] These filters, unlike permanent ones, feature a hook or retrieval mechanism allowing removal via a percutaneous procedure, typically from jugular or femoral access using snares, sheaths, or forceps once PE risk decreases.[1][2][6][7] Common designs include conical types like Günther Tulip (Cook Medical), Celect Platinum (Cook), Denali (Bard), and Option Elite (Argon), made from materials such as nitinol or cobalt-chromium, deployable via small sheaths (5F-9F) into IVCs up to 32 mm diameter.[3][5] Retrieval success rates exceed 90-99% in studies, though challenges arise with prolonged dwell times (>6 months), including filter tilt, strut penetration, thrombus entrapment, endothelialization, or embedding, sometimes requiring advanced techniques like loop snares or dual access.[2][3] Guidelines recommend retrieval when anticoagulation resumes safely, with low PE risk, and no ongoing filter indication, balancing in situ risks like caval thrombosis or fracture against procedural complications.[1] These devices expand treatment options for prophylactic or temporary VTE protection but are not therapeutic molecular targets.[1][2][3]
Beyond the preview
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Explore the programs pursuing this target and their development progress.
Follow the clinical studies evaluating therapies directed at this target.
Compare approaches across drug candidates, modalities, and indications.
Investigate the research and source evidence behind target biology and development.
Explore patent activity around therapies and technologies addressing this target.
Connect target biology, drug development, and emerging evidence in your research.
See how Gosset can support your research on Retrievable inferior vena cava filter (rIVCF).