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Rho GTPase activating protein 21 pseudogene

Molecular classification: Other (pseudogene)

Overview

The Rho GTPase activating protein 21 pseudogene (ENSG00000218418) is a non-functional genomic sequence related to the protein-coding gene ARHGAP21. Pseudogenes do not encode functional proteins and are not considered therapeutic or biological targets. Confusion arises because the protein-coding gene ARHGAP21 ("Rho GTPase-activating protein 21") is a bona fide enzymatic regulator in the Rho GTPase signaling pathway and is implicated in cytoskeletal organization, insulin secretion, and certain diseases, whereas the pseudogene is not involved in such pathways or pathologies.

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