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Rho GTPase activating protein 23 pseudogene 1 (ARHGAP23P1) is a human pseudogene, meaning it is a DNA sequence similar to a functional gene (in this case, ARHGAP23), but it does not encode a functional protein due to mutations or lack of appropriate regulatory elements. ARHGAP23P1 does not produce an active protein and has no known direct biological function or disease association. It is not considered a therapeutic target, receptor, enzyme, or signaling protein. The canonical gene, ARHGAP23, is a member of the RhoGAP family and regulates Rho GTPases which are involved in numerous cellular functions, but ARHGAP23P1 is distinguished as a noncoding pseudogene[4]. Notes: - ARHGAP23P1 is specifically annotated as a pseudogene and not as a protein-coding gene or functional target[4]. - There is nothing to indicate it plays a direct role in signaling, as a receptor, or in human disease biology; therefore, it cannot be considered a drug target, and no drugs, mechanisms of action, or safety concerns are applicable. - No evidence suggests ARHGAP23P1 is used as a biomarker. - The entry is considered not suitable as a druggable target or receptor nomenclature. - If you are referencing the functional Rho GTPase-activating protein 23, the target would be ARHGAP23 rather than ARHGAP23P1.
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