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Rhomboid domain containing 1 pseudogene
- Molecular classification
- Pseudogene, Other (non-coding RNA, not a protein-coding gene)
01
Overview
Rhomboid domain containing 1 pseudogene (ENSG00000219409, also known as AL590704.1 or LOC100420214) is a human pseudogene that is related to the protein-coding gene RHBDD1, which encodes a serine-type intramembrane protease. As a pseudogene, this locus does not code for an active protein and is considered non-functional at the protein level. Pseudogenes may have regulatory roles in gene expression, for instance by functioning as competitive endogenous RNAs, miRNA decoys, or sources of regulatory noncoding RNAs, though these functions are context-dependent and not established for this specific pseudogene. It is not considered a therapeutic target by current definition, nor is there evidence of it serving as a biomarker or being associated directly with disease or drug response in the literature.
- Other names
- AL590704.1LOC100420214Rhomboid domain containing 1 (RHBDD1) pseudogene
02
Biological functions
Possible regulation of gene expression via noncoding RNA mechanisms, such as miRNA decoy or source of regulatory RNAs for its parent gene (RHBDD1) or other targets
03
Disease associations
Other (pseudogenes in general have been implicated in cancer and other diseases through gene regulation, but there is no direct evidence for this specific pseudogene; the protein-coding RHBDD1 gene, not this pseudogene, is associated with some developmental disorders)
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