Rhophilin Rho GTPase binding protein 2 pseudogene

“Rhophilin, Rho GTPase binding protein 2 pseudogene” (RHPN2P1, ENSG00000259882) is classified as a pseudogene, meaning it does not encode a functional protein but may be a genomic remnant related to the actual RHPN2 gene. The true protein-coding homolog, RHPN2 (Rhophilin-2), binds RhoA and RhoB and is involved in actin cytoskeleton organization and signaling by Rho GTPases. Because pseudogenes generally do not have a protein product, they are not considered drug targets, do not play direct physiological roles, and are not involved in any therapeutic mechanism. The actual druggable or biologically relevant protein is Rhophilin Rho GTPase binding protein 2 (RHPN2), not the pseudogene. The pseudogene (RHPN2P1/ENSG00000259882) lacks evidence for a protein product or direct disease relevance. If your goal is structured data for therapeutic target assessment, RHPN2P1 should not be considered; use RHPN2 (ENSG00000131941) for scientific or drug discovery purposes. No aliases associated with drugs, biomarkers, or disease processes are available for RHPN2P1. ENSG00000259882 identifies a pseudogene and is not a valid therapeutic target. If you need details on the functional rhophilin-2 (RHPN2), refer to ENSG00000131941, which is involved in actin cytoskeleton regulation and Rho GTPase signaling.

Other names

Rhophilin Rho GTPase binding protein 2 pseudogene 1RHPN2P1Rhophilin pseudogeneENSG00000259882