Rhophilin Rho GTPase binding protein 2 pseudogene 1 (RHPN2P1)

Rhophilin Rho GTPase binding protein 2 pseudogene 1 (RHPN2P1) is classified as a pseudogene in humans and is not known to produce a functional protein product[3][6]. It is predicted to be involved in the negative regulation of stress fiber assembly but lacks demonstrated biological activity or clear disease associations[3]. As a pseudogene, RHPN2P1 is not considered a therapeutic target, and there are currently no drugs or biomarkers associated with it. Its role, if any, is likely limited to genomic or transcriptional regulation rather than direct protein function. Key points: - RHPN2P1 is a pseudogene, not a canonical gene coding for a functional protein[3][6]. - There is no evidence that it encodes a druggable target or participates in disease mechanisms as a direct effector. - Pseudogenes often have no biological function, but some may have regulatory impacts at the transcript level; this has not been demonstrated for RHPN2P1[3]. - Most databases (GeneCards, NCBI) clarify its pseudogene status and lack of association with established pathways, functions, disease roles, or pharmacology[3][6].

Other names

Putative rhophilin-2-like protein RHPN2P1Rhophilin-2 pseudogene 1