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Riboflavin (None)

Target: None
Molecular classification: Vitamin, Cofactor precursor

Overview

Riboflavin, also known as vitamin B2, is a water-soluble vitamin essential for human health. It is a precursor to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are involved in energy metabolism, cell respiration, and antioxidant defense. Riboflavin also plays a role in the metabolism of fats, carbohydrates, and proteins and helps maintain normal homocysteine levels. While generally safe, recent research suggests very high doses could promote tumorigenic progression under specific genetic contexts.

Other names: Vitamin B2Vitamin GLactoflavinHepatoflavinOvoflavin

Mechanism of action

Acts as a precursor to FMN and FAD, essential coenzymes in various metabolic processes and redox reactions. Also acts as an antioxidant.

Biological functions

Coenzyme precursor (FMN/FAD)Energy metabolismRedox reactionsGrowth/developmentRBC productionAntioxidant defenseMetabolism of fats, carbohydrates, and proteins

Disease associations

Riboflavin deficiency (Ariboflavinosis)High blood homocysteine levelsMigraine headachesCardiovascular risk (due to elevated homocysteine)Skin disordersAnemia

Safety considerations

Potential for tumorigenic progression at very high doses in specific genetic contexts (ALK+ NSCLC models) - requires further research.Foods containing riboflavin are destroyed by light exposure - foods should not be stored long-term in clear containers exposed to light.

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