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Ribonuclease A family member 12 (RNASE12) is a protein-coding gene located on human chromosome 14. It is classified as part of the ribonuclease A superfamily based on sequence but is predicted to be inactive and does not exhibit ribonuclease enzymatic activity. Some gene ontology predictions suggest it may participate in nucleic acid binding or in defense responses, but there are no established physiological functions or roles in disease, nor are there known interacting drugs or therapeutic applications. RNASE12 is not considered a pharmacological or therapeutic target. It lacks enzymatic function, has no known role in major disease processes, and there are no known drugs targeting it. The gene is also known by multiple aliases, largely reflecting its predicted family or historical/unverified annotations, but "Ribonuclease A family member 12 (inactive)" is the most accurate current descriptor.
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