Ribonuclease H1 pseudogene 2 (RNASEH1P2)

Ribonuclease H1 pseudogene 2 (RNASEH1P2) is a pseudogene related to the Ribonuclease H1 gene family. It is not a functional protein-coding gene, but rather a genomic locus with high sequence similarity to the active Ribonuclease H1 gene. This pseudogene does not produce a functional enzyme or receptor and is not known to have a biological function, disease association, or role as a therapeutic target. Ribonuclease H1 has several pseudogenes at distinct chromosomal locations, and these are sometimes incorrectly listed as protein-coding or functional targets[1][3]. Key context: - RNASEH1P2 refers to a pseudogene, meaning it does not produce a functional ribonuclease H1 protein or act as a druggable molecular target. - The "active" gene, Ribonuclease H1, is a DNA/RNA hybrid endonuclease with important roles in nucleic acid metabolism, but pseudogenes like RNASEH1P2 do not share these properties or relevance in disease or therapy[1][3][5]. - Genomic pseudogenes associated with RNASEH1 are found at multiple locations, commonly on chromosomes 2, 17, and 1[1][3]. Summary: RNASEH1P2 is a non-functional pseudogene and not a valid therapeutic or biological target. If you are seeking information about the biologically active enzyme, see "Ribonuclease H1" (RNASEH1), which is functionally and clinically distinct[1][3][5].

Other names

RNASEH1P2