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Ribonucleoprotein Complex (RNP)

Target: RNP
Molecular classification: RNA-binding protein complex

Overview

A ribonucleoprotein complex (RNP) is a molecular assembly composed of RNA molecules bound to one or more RNA-binding proteins (RBPs). These complexes are fundamental to cellular biology, mediating a wide range of processes involving the synthesis, processing, modification, transport, and regulation of RNA. Examples include ribosomes, telomerase, spliceosomal snRNPs, vault particles, and RNase P. Defects in specific ribonucleoprotein complexes can lead to genetic disorders, highlighting their importance and making them potential therapeutic targets.

Other names: RNP particleRibonucleoprotein particlemRNA ribonucleoproteinmRNP

Biological functions

Transcription regulationTranslationRNA processing (splicing, modification)RNA transportRNA localizationRNA stability regulationmRNA storagemRNA degradationTelomere maintenance

Disease associations

Genetic disorders affecting splicingGenetic disorders affecting translationGenetic disorders affecting telomere maintenance

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