Ribosomal protein L12 pseudogene 21 (RPL12P21)

Ribosomal protein L12 pseudogene 21 (RPL12P21) is a processed pseudogene derived from the RPL12 gene, which codes for a component of the large 60S ribosomal subunit involved in protein synthesis[1][2][3]. Pseudogenes like RPL12P21 are non-functional genomic segments that resemble protein-coding genes but typically lack the ability to encode functional proteins due to accumulated mutations[1][3]. There is no evidence that RPL12P21 is expressed or has any established biological, disease, or therapeutic relevance in humans. It is not a receptor, enzyme, transporter, or other type of drug target. The parent gene, RPL12, encodes a ribosomal protein that is a structural constituent of the ribosome and part of the L11P family[1][3]. However, pseudogenes such as RPL12P21 result from the duplication or retrotransposition of the parental gene and have lost their protein-coding capacity. Multiple processed pseudogenes for ribosomal protein genes are common in the genome, but these are not functional and do not participate in cellular processes[1][3]. Pseudogenes are not considered valid therapeutic targets, and there is no evidence for drug interactions, disease roles, or use as biomarkers. If you intended to refer to the functional ribosomal protein, use "Ribosomal protein L12 (RPL12)", not the pseudogene.

Other names

RPL12 pseudogene 21ribosomal protein L12 processed pseudogene 21