Ribosomal protein L12 pseudogene 37 (RPL12P37)

Ribosomal protein L12 pseudogene 37 (RPL12P37) is a processed pseudogene in humans, named for its sequence similarity to the functional RPL12 gene, which encodes the 60S ribosomal protein L12[4][5]. Unlike the canonical RPL12 gene, RPL12P37 does not encode a functional protein; it is classified as a pseudogene, meaning it is a remnant of a gene that has lost its protein-coding ability or is otherwise nonfunctional[5]. This pseudogene is annotated in the human genome (NCBI Gene ID: 100129801), with genome location on chromosome 17[5]. Pseudogenes like RPL12P37 do not have established roles as therapeutic targets, do not participate in known molecular signaling, and are not associated with drug interactions, disease roles, or biomarker functions[1][5]. Their main relevance is for genomic annotation and studies of gene family evolution.\n\nClarification: There is nothing misleading in the nomenclature or basic identity, but RPL12P37 is a pseudogene, not a functional protein-coding gene or therapeutic target. This distinguishes it clearly from the functional ribosomal protein L12 (RPL12), which is an essential component of the 60S ribosomal subunit[1][3][4][5].

Other names

RPL12_18_1579RPL12P37