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RPL12P8 (Ribosomal protein L12 pseudogene 8) is a human pseudogene related to the ribosomal protein L12 gene, located in the genome as a non-coding DNA sequence[1][2][9]. Pseudogenes like RPL12P8 are remnants of once-functional genes that have lost their protein-coding ability, typically due to mutations. RPL12P8 does not encode a functional protein, is not part of any known therapeutic, signaling, or enzymatic pathway, and is not considered a therapeutic target or disease gene. Its presence is attributed to genomic duplication events and is generally of interest only in genome annotation, not drug development or clinical biomarker research[1][2][9].\n\n**Note:** \nConfusion may arise from similarity to the functional **RPL12** gene (ribosomal protein L12), which encodes a component of the 60S ribosomal subunit involved in protein synthesis[3][8]. However, RPL12P8 itself is categorically a pseudogene and does not represent a drug target or provide a therapeutic function.
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