Ribosomal protein L14 pseudogene 1 (RPL14P1)

**Ribosomal protein L14 pseudogene 1 (RPL14P1)** is a processed pseudogene in the human genome that is homologous to the functional ribosomal protein L14 gene (RPL14). Pseudogenes like RPL14P1 arise through the duplication and subsequent mutation of active genes, resulting in gene copies that lack the ability to produce functional proteins. RPL14P1 does not code for a biologically active protein, so it does not participate in ribosome structure or function and is not implicated as a therapeutic target. RPL14P1 is catalogued in major gene databases (HGNC: 31384, NCBI Gene: 144581, Ensembl: ENSG00000139239) and is sometimes referred to by aliases such as RPL14L and bcm1298[5][7][6]. **Notes**: - RPL14P1 is a pseudogene—it does not encode a protein and has no known functional role in biology or disease, nor is it a receptor, enzyme, transporter, or therapeutic target[5][7]. - The naming overlaps with the nearby active gene **RPL14** ("60S ribosomal protein L14") but refers specifically to an inactive, non-protein-coding locus. - There are no known disease associations, mechanisms of action, or drugs that target RPL14P1, nor any biomarker or safety data relating to this pseudogene. - Aliases sometimes include the name of the functional ribosomal protein (**60S ribosomal protein L14**), but for precision, the pseudogene itself is distinct and nonfunctional.

Other names

bcm129860S ribosomal protein L14RPL14LRPL14_1_1246