Ribosomal protein L17 pseudogene 45 (RPL17P45)

Ribosomal protein L17 pseudogene 45 (RPL17P45) is a processed pseudogene derived from the ribosomal protein L17 (RPL17) gene. Pseudogenes like RPL17P45 resemble protein-coding genes but are nonfunctional, typically as a result of mutations or lack of regulatory sequences required for protein expression. There is no evidence for protein product, therapeutic targeting, or any physiological or disease-related role for this specific pseudogene. It does not act as a receptor, enzyme, transporter, or transcriptional regulator, and its presence is largely considered a non-functional genomic element[1][3][9][10]. RPL17P45 should not be confused with its parent gene, RPL17 (ribosomal protein L17), which encodes a structural component of the ribosomal 60S subunit and is associated with core cellular processes like protein synthesis[4][7]. However, RPL17P45 itself is a noncoding, nonfunctional derivative. Pseudogenes can sometimes play a regulatory role (such as serving as competitive endogenous RNAs), but there is no evidence in the scientific literature for any such function for RPL17P45 specifically[2]. This distinguishes it from a small subset of actively transcribed or functional pseudogenes implicated in disease or biology. RPL17P45 is not a drug target or functional gene: it is an annotated genomic pseudogene that does not encode a protein, has no known function, and is not therapeutically relevant[1][9][10]. Its designation as a "target" is incorrect.

Other names

RPL17_16_1598RPL17P45

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