Ribosomal protein L18 pseudogene 10 (RPL18P10)

Ribosomal protein L18 pseudogene 10 (RPL18P10) is a processed pseudogene in the human genome, derived from the parent gene RPL18 that encodes the ribosomal protein L18, a component of the 60S large ribosomal subunit. Unlike functional protein-coding genes, RPL18P10 does not encode a protein product and is classified among the "processed pseudogenes," which are abundant in the genome as remnants of RNA retrotransposition events. RPL18P10 does not have known functions, does not participate in cellular or disease pathways, and is not considered a target for drug action or a biomarker[5][6][7]. RPL18P10 appears in human gene databases strictly as a pseudogene and not as an active, functional gene or receptor. Pseudogenes like RPL18P10 lack protein-coding ability, usually arising from retrotransposition or gene duplication events, and typically have sequence similarities to their "parental" protein-coding genes but contain mutations or frame disruptions that prevent translation into functional proteins[5][6][7]. Ribosomal protein L18 (RPL18) is a critical structural component of the 60S ribosomal subunit and is involved in protein synthesis[1][2], but the suffix "pseudogene 10" indicates this is a non-functional genomic copy related to RPL18 and not itself participating in ribosomal activity or any known pathways. Large numbers of ribosomal protein pseudogenes exist in the human genome, often annotated due to sequence similarity but specifically noted as non-functional, with no known biological role or implication in disease[6][7]. No drugs, disease associations, or safety concerns are recorded for RPL18P10. RPL18P10 is a non-functional processed pseudogene representing a remnant of the ribosomal protein L18 gene, not a genuine molecular target in therapeutic, diagnostic, or research contexts[5][6][7].

Other names

RPL18_6_1311RPL18P10