ribosomal protein L21 pseudogene 120 (RPL21P120)

ribosomal protein L21 pseudogene 120 (RPL21P120) is a processed pseudogene in the human genome, associated with, but functionally distinct from, ribosomal protein L21 (RPL21)[6]. Unlike RPL21, which encodes a bona fide protein component of the ribosomal 60S subunit, the RPL21P120 locus does not encode a functioning protein and is not expressed as a ribosomal protein. Pseudogenes like RPL21P120 typically arise from gene duplication or retrotransposition events and may share sequence similarity with the parent gene but lack biological function due to sequence changes or truncations. They are not considered therapeutic targets, biomarkers, or involved in disease or drug mechanisms. The presence of multiple ribosomal protein pseudogenes in the genome is common and they are generally not clinically or pharmacologically relevant[6][1][7]. *RPL21P120* is **not a therapeutic target**, receptor, enzyme, transporter or gene product with specific biological or disease associations[6]. It is **incorrect** as a drug target: it is a pseudogene, not a functional ribosomal protein or clinically actionable molecule. Aliases include RPL21_57_1527, RPL21P120. Molecular classification: Other (*pseudogene*; not an enzyme, receptor, ion channel, etc.). No biological or disease functions are attributed to this pseudogene. No drugs, mechanism of action, biomarkers, or safety concerns are associated with this locus. For the actual protein-coding gene (RPL21), see *ribosomal protein L21* — a well-characterized component of the ribosome potentially involved in cell proliferation and certain hereditary diseases, but pseudogenes like RPL21P120 do not share these attributes[1][5][6][7].

Other names

RPL21_57_1527RPL21P120