Ribosomal protein L21 pseudogene 25 (RPL21P25)

RPL21P25 is a processed pseudogene related to the genuine ribosomal protein L21 gene. Pseudogenes like RPL21P25 are DNA sequences that resemble their parent protein-coding genes but contain mutations or sequence differences that render them nonfunctional for protein coding[2][6]. However, ribosomal protein pseudogenes can play *regulatory roles* at the RNA level, such as modulating the expression of their parent genes via RNA interference or via acting as competitive endogenous RNAs that bind microRNAs[2]. Functional RPL21 (not the pseudogene) encodes a protein that is part of the 60S ribosomal subunit critical for protein synthesis, with roles in cell proliferation and disease; its pseudogenes instead might influence related gene expression but do not themselves code for functional ribosomal protein[5][3][6]. Summary of classification: - RPL21P25 is not a canonical therapeutic target and should not be conflated with the functional ribosomal protein L21 gene. - Structured annotations for pseudogenes (like aliases, classification, biomarkers, interacting drugs) are generally very sparse because they do not serve as classical drug targets or clinical biomarkers[6]. - Any biological or disease relevance would be indirect and regulatory, not via encoded protein function[2].

Other names

RPL21_5_46RPL21P25