Ribosomal protein L21 pseudogene 53 (RPL21P53)

RPL21P53 is a processed pseudogene related to the human RPL21 gene, which encodes 60S ribosomal protein L21, a structural component of the cytoplasmic ribosome. Pseudogenes like RPL21P53 arise from duplication or retrotransposition events and do not produce functional proteins. While ribosomal protein pseudogene expression may be dysregulated in some diseases and could reflect cell proliferation or stress (as reported for similar pseudogenes), there is no evidence that RPL21P53 itself functions as a therapeutic target or biomarker. Some ribosomal protein pseudogenes may affect gene regulation, but their roles are often speculative and not well characterized. RPL21P53 is not a canonical target for drug development as it does not encode a functional ribosomal protein or receptor. The name and abbreviation are correctly formatted, but the molecule is often confused with its protein-coding parent gene, RPL21; this is an important distinction for structured database curation. If you need information on the functional ribosomal protein itself, refer to RPL21 (ribosomal protein L21), which is protein-coding and associated with ribosome structure and certain genetic diseases.

Other names

RPL21_19_517RPL21P53