Ribosomal protein L21 pseudogene 62 (RPL21P62)

Ribosomal protein L21 pseudogene 62 (RPL21P62) is a processed pseudogene related to the gene encoding ribosomal protein L21, a component of the 60S subunit of the ribosome. Pseudogenes are generally considered non-functional remnants of once-functional genes, typically lacking protein-coding capacity, and do not produce an active ribosomal protein product[1][3][5]. While there are over 80 ribosomal proteins, many of their genes have multiple pseudogenes dispersed in the genome—these do not fulfill the essential biological roles of their parent protein-coding genes[1][3][4]. Most pseudogenes, including those related to ribosomal proteins, are transcriptionally inactive and lack known biological function or direct disease association[3]. - The parent gene, **RPL21**, encodes a protein involved in ribosome structure and function, and mutations in **RPL21** are linked to diseases such as Hypotrichosis simplex of the scalp[1]. This does **not** extend to RPL21P62, which is a non-coding pseudogene. - It is not standard practice to refer to pseudogenes as drug targets or assign them classical target biology features unless specific regulatory or functional properties have been experimentally demonstrated, which is not indicated here[3]. - Any references to drugs, mechanisms of action, or disease roles are relevant only to the parental gene, not the pseudogene described here[1][5].

Other names

RPL21_23_656RPL21P62