Ribosomal protein L21 pseudogene 83 (RPL21P83)

Ribosomal protein L21 pseudogene 83 (RPL21P83) is one of several processed pseudogenes related to ribosomal protein L21 found in the human genome. Pseudogenes such as RPL21P83 are non-functional, meaning they do not code for a protein and lack active biological roles. The functional ribosomal protein L21 (RPL21) is a component of the 60S ribosomal subunit involved in protein synthesis and cell proliferation, but its pseudogenes, including RPL21P83, have no known direct clinical, biochemical, or pharmacological significance[1][5].\n\nThe functional version, RPL21, is implicated in hair follicle biology and cell proliferation, with mutations causing disorders such as hereditary hypotrichosis simplex[5]. These roles do not apply to the pseudogene RPL21P83, which is not expressed as functional protein, is not classified as a drug target, and does not interact with drugs or act as a biomarker[1][5].

Other names

RPL21_31_978RPL21P83