Ribosomal protein L21 pseudogene 86 (RPL21P86)

Ribosomal protein L21 pseudogene 86 (RPL21P86) is a non-functional genomic sequence derived from the ribosomal protein L21 gene. Pseudogenes like RPL21P86 do not encode functional proteins and are generally considered evolutionary remnants without direct biological roles. However, a minority of pseudogenes can be transcribed as non-coding RNAs and participate in gene regulation, typically through mechanisms like mRNA stability modulation, antisense transcription, or as microRNA decoys, but no specific regulatory function is documented for RPL21P86 itself[1][6][7]. The parent gene, RPL21, encodes a structural component of the 60S large ribosomal subunit and is essential in protein synthesis, but RPL21P86 is distinct from and does not perform this role[1][3][5]. RPL21P86 is annotated in databases, such as GeneCards, BioGPS, and the GWAS Catalog, as a pseudogene located on chromosome 9q22.31[1][6][8]. There are no known therapeutic applications, disease associations, or interacting drugs for this pseudogene[1][5][8]. In summary, RPL21P86 is a processed pseudogene, not a therapeutic target, and is not associated with any established physiological or pathological roles.

Other names

RPL21_34_998RPL21P86

Not applicable; there are no drugs targeting this pseudogene.