Target intelligence / Profile preview

Ribosomal protein L22 pseudogene (RPL22P)

Target
RPL22P
Molecular classification
Other, Pseudogene, Ribosomal protein (pseudogene family)
01

Overview

The "ribosomal protein L22 pseudogene" designates one of several genomic loci that are processed pseudogenes (non-functional DNA sequences) highly homologous to the ribosomal protein L22 gene (RPL22)[2][8]. Pseudogenes are typically the result of genomic duplication or retrotransposition events and do not encode functional proteins. While the functional RPL22 gene encodes a cytoplasmic component of the large ribosomal subunit 60S, facilitating protein synthesis and possibly playing roles in immune response and oncogenesis, its pseudogenes (including ENSG00000270776) do not have protein-coding function. There is no known direct biological function or clinical relevance for these pseudogenes. Any reference associating this pseudogene with therapeutic action or disease is likely due to misunderstanding with the parent RPL22 gene[2][8]. Key note: If you are searching for an *active* ribosomal protein, the correct entry is "Ribosomal protein L22" (RPL22), and not its pseudogenes. Pseudogenes such as the one referenced here are generally not relevant as drug targets or for direct biological function in humans[2][8].

Other names
ribosomal protein L22 pseudogene 1EBER-associated protein pseudogene 1Epstein-Barr virus small RNA-associated protein pseudogene 1Epstein-Barr-encoded RNA-associated protein pseudogene 1
02

Mechanism of action

None (not a target for drugs; no mechanism of action applies)

03

Biological functions

Other (Pseudogenes are typically non-functional; they do not have biological functions at the protein level. Some rare pseudogenes can be transcribed or have regulatory roles, but no strong evidence supports functional roles for this entry in humans.)
04

Disease associations

Other (pseudogenes are generally not associated with direct disease roles; any disease association typically results from confusion with the parent gene, RPL22)

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