Ribosomal protein L22 pseudogene 5 (RPL22P5)

Ribosomal protein L22 pseudogene 5 (RPL22P5) is a processed pseudogene corresponding to the functional ribosomal protein L22 gene (RPL22) in humans[1][5][7]. As a pseudogene, RPL22P5 is a non-functional genomic sequence that resembles the RPL22 gene but does not encode a functional protein. It arose through retrotransposition and is among numerous dispersed pseudogenes related to ribosomal protein genes in the human genome[2][1]. Pseudogenes like RPL22P5 do not have established biological functions, do not act as therapeutic drug targets, and are not implicated in disease mechanisms or biomarker utility[1][7]. Key points: - RPL22P5 is not a protein-coding gene and does not produce a functional protein[1][7]. - It is not a valid therapeutic target, receptor, enzyme, or transporter[1][7]. - There is sometimes confusion because the parent gene (RPL22) is a true ribosomal protein and may be involved in certain disease contexts, but RPL22P5 specifically is a non-coding pseudogene[4][1][7]. - Pseudogenes like RPL22P5 are generally excluded from target-based therapeutic drug development efforts and do not have assigned molecular functions or disease roles. Note: RPL22P5 is often listed in genomic catalogs, but inclusion as a molecular target is incorrect unless there is evidence (not currently available) for a functional RNA product or regulatory activity[1][2][7]. The main functional gene is Ribosomal protein L22 (RPL22), not the pseudogene.

Other names

RPL22_2_96RPL22P5