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RPL23AP12, ribosomal protein L23a pseudogene 12, is a processed pseudogene resulting from genomic duplication and mutation of the ribosomal protein L23a gene. Unlike its parent gene, RPL23AP12 does not encode a functional protein and is classified as a non-coding pseudogene. Such pseudogenes frequently arise from gene duplication events and may be present in human and other species’ genomes. While certain ribosomal protein L23a pseudogenes (e.g., RPL23AP53) have been investigated for their expression patterns and possible associations with cancer progression or prognosis in studies, there is no evidence that RPL23AP12 itself plays a functional biological role or is targeted by drugs[1][2][3]. Thus, RPL23AP12 is not considered a canonical therapeutic target and should not be listed as a receptor or drug target. Care should be taken to avoid confusion with functional ribosomal proteins or other pseudogenes that may be biologically relevant.
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