Target intelligence / Profile preview

Ribosomal protein L23a pseudogene 24 (RPL23AP24)

Target
RPL23AP24
Molecular classification
Other (processed pseudogene)
01

Overview

RPL23AP24 is not a functional target; it is a pseudogene of the ribosomal protein L23a (RPL23A). Pseudogenes are DNA sequences similar to known genes but typically non-functional—they do not encode a functional protein. RPL23AP24 is listed in genomic and reagent catalogs as a pseudogene and is not reported as functionally expressed or targeted by therapeutics. Ribosomal protein L23a pseudogene 24 (RPL23AP24) is a processed pseudogene related to the RPL23A gene, which encodes a 60S ribosomal protein involved in protein synthesis as part of the large ribosomal subunit. RPL23AP24 itself does not produce a functional protein and is not involved in any known biological processes or therapeutic pathways. The human genome contains multiple processed pseudogenes of ribosomal genes like RPL23A, including RPL23AP24, which are typically non-expressed genomic relics formed by gene duplication or retrotransposition events. Pseudogenes do not generally produce proteins, though some can have regulatory roles; there is no evidence that RPL23AP24 has biological activity or is involved in disease. The protein-coding gene RPL23A (not the pseudogene) has been implicated in ribosome structure and, in rare cases, as an autoimmune target or in human disease, but not its pseudogenes. Related pseudogenes, such as RPL23AP53, have been subject to research for regulatory or biomarker roles in specific cancers; no such data exist for RPL23AP24. In summary: RPL23AP24 is a processed pseudogene of RPL23A, with no known function, targetability, or disease role, and should not be considered a canonical therapeutic target.

Other names
RPL23A_1_2RPL23AP24

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