Ribosomal protein L23a pseudogene 27 (RPL23AP27)

Ribosomal protein L23a pseudogene 27 (RPL23AP27) is a processed pseudogene in the human genome. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they are often products of gene duplication or retrotransposition. RPL23AP27 shares sequence similarity with the functional ribosomal protein L23a gene (RPL23A) but does not produce a functional protein. There is no evidence that this pseudogene encodes a protein, plays a direct biological role, or is therapeutically actionable. It is cataloged in major gene databases as a pseudogene, with no protein product or known biological function. The parent gene RPL23A encodes a component of the large (60S) ribosomal subunit and has distinct known biological functions and disease associations, but RPL23AP27 itself does not share these roles. Pseudogenes like RPL23AP27 may be transcribed in some contexts, but their transcripts are generally considered non-coding and are not targets for drug development. Multiple pseudogenes are derived from ribosomal protein genes and are typically designated RPL23AP[n], where [n] is the pseudogene number. There are no documented drugs, disease associations, or biomarker applications for RPL23AP27 specifically.

Other names

RPL23A_10_252RPL23AP27