ribosomal protein L23a pseudogene 40 (RPL23AP40)

RPL23AP40 is a processed pseudogene in the human genome derived from the ribosomal protein L23a (RPL23A) gene, with the typical properties of ribosomal protein pseudogenes—namely, lack of protein coding potential. Such pseudogenes may have regulatory roles or be expressed as non-coding RNA, but there is no specific evidence for RPL23AP40 itself in biological function or disease. This locus is not a therapeutic target, druggable entity, or receptor. Pseudogenes like RPL23AP40 may be cataloged due to their sequence similarity to functional proteins but are typically excluded from lists of valid drug targets or receptors[6][8]. Key points and context: - RPL23AP40 is formally included in genomic databases as a processed pseudogene; it does not produce a functional protein and lacks known receptor, enzyme, or transporter activity[6][8]. - Other ribosomal protein L23a pseudogenes (e.g., RPL23AP53) have been studied as biomarkers in cancer research, but this is specific to certain pseudogenes and not documented for RPL23AP40 itself[2]. - The true ribosomal protein L23a (RPL23A) is a functional protein of the cytoplasmic ribosomal 60S subunit and does play cellular roles, but its pseudogenes (including RPL23AP40) are not considered functional or actionable targets[1][3][7]. In summary: RPL23AP40 is a non-coding pseudogene, not a therapeutic or actionable biological target, and should not be confused with the functional ribosomal protein L23a (RPL23A). There is no current evidence implicating RPL23AP40 in disease, drug interaction, or as a biomarker.

Other names

ribosomal protein L23A pseudogene 40RPL23A_17_408