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Target intelligence / Profile preview
Ribosomal protein L23a pseudogene 47 (RPL23AP47)
- Target
- RPL23AP47
- Molecular classification
- Other (processed pseudogene)
01
Overview
RPL23AP47 (Ribosomal protein L23a pseudogene 47) is a _processed pseudogene_ located in the human genome. It is part of a large family of ribosomal protein L23a pseudogenes dispersed throughout the genome, which are remnants of gene duplication or retrotransposition events. Unlike its parental gene, RPL23A, which encodes a component of the ribosomal 60S subunit, RPL23AP47 does _not encode_ a functional protein and has no known biological function[3][7][8]. Pseudogenes like RPL23AP47 are generally transcriptionally silent but can sometimes be used as markers in genome studies or as controls. There is no evidence supporting a direct role for RPL23AP47 in disease, nor utility as a therapeutic target or biomarker.
- Other names
- RPL23AP47RPL23A_21_778Ribosomal protein L23a pseudogene 47
02
Mechanism of action
None; not a target for pharmacological action.
03
Biological functions
None directly attributed; as a pseudogene, RPL23AP47 does _not_ encode a functional protein and thus is generally not involved in canonical biological processes[2][3][4][8].
04
Disease associations
None established; while some ribosomal protein pseudogenes (e.g., RPL23AP53) have differential expression in cancer (such as melanoma), there is _no direct evidence_ implicating RPL23AP47 in disease biology or therapeutics[7][8].
05
Safety considerations
None; it is not a drug target and has no recognized safety or toxicity issues.
06
Interacting drugs
None known; there are _no drugs_ targeting RPL23AP47, as it does not encode a functional molecule[2][3][4].
07
Biomarkers
None established; pseudogenes rarely serve as biomarkers unless proven otherwise, and no reports mention RPL23AP47 in this context[7].
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