Target intelligence / Profile preview

Ribosomal protein L23a pseudogene 54 (RPL23AP54)

Target
RPL23AP54
Molecular classification
Other (pseudogene)
01

Overview

Ribosomal protein L23a pseudogene 54 (RPL23AP54) is a processed human pseudogene related to the ribosomal protein L23a family. As a pseudogene, it lacks coding capacity for a functional protein, and there is no evidence that this locus plays a direct biological or therapeutic role. Pseudogenes of ribosomal proteins are common, and, while some may have regulatory or transcriptomic importance, RPL23AP54 has not been specifically linked to disease, biomarker status, or drug interactions. Its principal identifiers include RPL23AP54 and the synonym RPL23A_22_870. No evidence supports consideration of RPL23AP54 as a therapeutic target or direct contributor to disease biology in well-documented sources[7][8][9][6]. GeneCards, BioGPS, and WikiGenes list RPL23AP54 solely as a pseudogene, with no associated protein, function, or disease information[7][8][6]. Related *functional* gene (RPL23A) encodes a structural ribosomal protein; its pseudogenes, including RPL23AP54, are generally non-coding, though other family members (such as RPL23AP53) have occasionally been studied for association with gene expression changes in cancer, not as direct drug targets or biomarkers[5]. No evidence from any search result indicates RPL23AP54 codes for a protein, interacts with drugs, or otherwise qualifies as a therapeutic target.

Other names
RPL23A_22_870RPL23AP54[9][7][8][6]
02

Biological functions

Other (no known direct biological function as a protein; may have regulatory roles as a pseudogene or non-coding RNA, but not well characterized for this specific pseudogene)
03

Disease associations

Other (no known direct role for RPL23AP54; related pseudogenes such as RPL23AP53 have been analyzed in cancer transcriptomic analyses, but not RPL23AP54 specifically)[5]

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