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RPL23AP61 (ribosomal protein L23a pseudogene 61) is a processed pseudogene found in the human genome, corresponding to the functional gene RPL23A, which encodes the ribosomal protein L23a—a structural component of the 60S ribosomal subunit in the cytoplasm[1][3][4]. Processed pseudogenes are sequence remnants of functional genes that generally do not encode functional proteins due to accumulated mutations or lack of regulatory elements. RPL23AP61 does not produce RNA or protein products and is not involved in known biological pathways, nor is it considered a druggable or therapeutic target[1][4]. While some ribosomal protein L23a pseudogenes (such as RPL23AP53) have been correlated with gene expression changes in cancer and immune-related profiles[2], there is no evidence that RPL23AP61 itself is functionally involved in disease or drug response. Key points: - Not a functional protein; lacks coding capacity. - Not a therapeutic target; not a receptor, enzyme, transporter, or transcription factor. - No direct role in disease, biomarkers, or drug mechanisms. - Common aliases include RPL23A_22_1044 and RPL23AP61[1][4]. - Belongs to the class 'processed pseudogene'.[1][4] If structured information is needed for another ribosomal L23a pseudogene (such as RPL23AP53), which is being studied in cancer contexts[2], please specify, as findings for that target cannot be directly transferred to RPL23AP61.
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