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Ribosomal protein L23a pseudogene 62 (RPL23AP62) is a processed pseudogene in the human genome that is derived from the parental gene RPL23A, which encodes a component of the 60S subunit of the ribosome. Pseudogenes such as RPL23AP62 do not produce functional proteins and typically arise through retrotransposition or genomic duplication. There is no evidence that RPL23AP62 has a direct protein-coding function or established biological role, nor is it considered a therapeutic target. Its designation as a pseudogene means it is generally used for genomic, evolutionary, or transcriptomic studies and not as a drug target or biomarker in clinical contexts. Gene location: Chromosome 17:6251298-6251842. Official gene identifiers: HGNC:36276, NCBI Gene: 100271617, Ensembl: ENSG00000213233. Nature and significance: Being a processed pseudogene, RPL23AP62 is not translated into a functional protein and has no confirmed physiological or pathological function. Distinction: This entity should not be confused with functional ribosomal proteins or ribosomal protein L23a pseudogenes with known regulatory functions described in disease, such as RPL23AP53 in melanoma; there is no such evidence or literature for RPL23AP62. Therapeutic relevance: RPL23AP62 is not a drug target, is not implicated in disease, and there are no drugs, biomarkers, or safety concerns associated with it.
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