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Ribosomal protein L23a pseudogene 65 (RPL23AP65) is a processed pseudogene related to the ribosomal protein L23a gene family. Pseudogenes like RPL23AP65 do not encode functional proteins and are often regarded as genomic "fossils," though emerging research shows some ribosomal protein pseudogenes might be expressed and have regulatory functions in certain cell types or cancers[4]. However, RPL23AP65 itself is not described as contributing to protein synthesis, disease pathology, or drug response. The canonical gene, RPL23A, encodes a cytoplasmic component of the 60S ribosomal subunit, essential for protein synthesis, but RPL23AP65 is one of over 90 related pseudogenes in the human genome[3]. There is no evidence in the literature or databases for direct disease associations, therapeutic targeting, drug interactions, or established biomarker status for RPL23AP65. Note: If you intended the canonical *protein-coding* ribosomal protein L23a (RPL23A), refer to the ribosomal protein itself as a potential autoimmune target, cancer biomarker in some contexts, and structural ribosome component[3][5]. The specific term *RPL23AP65* refers unequivocally to a non-functional pseudogene, not a direct drug target[3].
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