Ribosomal protein L23a pseudogene 67 (RPL23AP67)

Ribosomal protein L23a pseudogene 67 (RPL23AP67) is a processed pseudogene of the ribosomal protein L23a gene. Like other ribosomal pseudogenes, it does not encode a functional protein and is considered non-coding. Processed pseudogenes arise from retrotransposition of mRNA from their parent genes and are generally transcriptionally inactive, although some ribosomal pseudogenes may have regulatory functions in certain tissues or disease states[3][5][6]. There is no evidence that RPL23AP67 functions as a therapeutic target, nor is it implicated as a direct disease-associated gene or biomarker. Confusion may arise due to the functional and disease roles of its parent gene RPL23A and other ribosomal pseudogenes in cancer and autoimmune diseases[2][5]. Key context: - RPL23AP67 is distinct from RPL23A (the protein coding gene encoding a 60S ribosomal subunit protein)[5][7]. - Large numbers of ribosomal protein pseudogenes exist in the human genome[2][5]. - Some ribosomal protein pseudogenes have been studied for roles in cancer regulation and as potential biomarkers, but this is not established for RPL23AP67[2]. In summary, RPL23AP67 is not a receptor or therapeutic target, but a non-coding pseudogene with no documented biological or clinical function, and its inclusion as a target is incorrect[3][5][6].

Other names

RPL23A_31_1299RPL23AP67