Ribosomal protein L23a pseudogene 83 (RPL23AP83)

Ribosomal protein L23a pseudogene 83 (RPL23AP83) is a non-protein-coding pseudogene identified in the human genome[3][4][6]. It is part of a large family of pseudogenes derived from the ribosomal protein L23a gene, which is involved in ribosome assembly and protein synthesis[7]. RPL23AP83 itself does not produce a functional protein and has no directly established biological function or disease associations. Unlike the parental RPL23A gene, which has roles in ribosome structure, RNA binding, and is associated with conditions such as Diamond-Blackfan anemia, pseudogenes such as RPL23AP83 primarily exist as genomic sequences and are not typically considered targets for therapeutic intervention[3][4][6][7]. Recent research on other ribosomal protein L23a pseudogenes (especially RPL23AP53) indicates some potential roles in cancer biology, immune modulation, and cell cycle regulation through regulatory RNA functions, but no such evidence currently exists for RPL23AP83 specifically[5]. Pseudogenes like RPL23AP83 may serve as molecular sponges for miRNAs or play other subtle regulatory roles, but these remain unproven and largely speculative[5]. RPL23AP83 is a pseudogene with no direct protein product, biological function, drug interaction, or established disease role. It is not a therapeutic target, although related elements in its family have shown some research interest in cancer contexts, mainly as correlates rather than drivers or targets[3][4][5][6][7].

Other names

RPL23A_38_1781RPL23AP83