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The **ribosomal protein L26 pseudogene 23** (RPL26P23, ENSG00000234450) is a processed pseudogene found in the human genome and shares sequence similarity with the protein-coding gene for ribosomal protein L26. Pseudogenes such as RPL26P23 arise from duplication or retrotransposition of functional ribosomal protein genes but have acquired disabling mutations (such as stop codons or frameshifts) that prevent them from producing active protein[2][4][6][9][10]. These elements are typically scattered throughout the genome and do not encode functional proteins; instead, they may serve as genomic fossils or, rarely, sources for regulatory RNAs. RPL26P23 is not associated with any known disease processes or therapeutic targeting. **Key facts:** - RPL26P23 does not code for a functional protein. - It is a member of the large family of ribosomal protein pseudogenes in the human genome, specifically related to the RPL26 ribosomal protein[6]. - It is not a therapeutic target and has no known role in disease, drug binding, or cellular pathways[2][9][10]. - This entry should not be used when seeking actionable drug targets or functional molecular entities. If a functional ribosomal protein L26-like entity is required, the relevant gene is **RPL26L1 (Ribosomal protein L26 like 1)**, which is a protein-coding gene and not a pseudogene[5][7].
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