Ribosomal protein L27 pseudogene 12 (RPL27P12)

RPL27P12 (ribosomal protein L27 pseudogene 12) is a processed pseudogene in the human genome related to the ribosomal protein L27 gene (RPL27). Unlike its parent gene, RPL27P12 does not code for an active ribosomal protein; its sequence is similar in structure but contains disabling mutations that render it non-functional. Like other ribosomal pseudogenes, it has arisen through retrotransposition but is simply a remnant of the protein-coding gene with no current role in protein synthesis or other cellular functions[2][3]. Pseudogenes of ribosomal proteins are frequent in the human genome and are neither expressed nor capable of producing functional proteins[2][3]. RPL27P12 is a pseudogene, not a therapeutic target, and does not participate in any known molecular pathways or diseases. All entries on interacting drugs, function, or disease relevance should be considered null. If a functional ribosomal protein L27 is desired—refer to RPL27, not its pseudogene relatives such as RPL27P12[1][6].

Other names

RPL27_4_1293RPL27P12