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Ribosomal protein L28 pseudogene 5 (RPL28P5)
- Target
- RPL28P5
- Molecular classification
- Other (processed pseudogene; not a member of canonical protein classes like receptor, enzyme, etc.)
01
Overview
Ribosomal protein L28 pseudogene 5 (RPL28P5) is a processed pseudogene representing a nonfunctional copy of the RPL28 gene, which encodes a structural constituent of the 60S ribosomal subunit[2][8]. While a portion of ribosomal protein pseudogenes may be transcribed and rarely translated into peptides, in most cases these RNAs and any peptides produced are not biologically meaningful, and the pseudogene itself has no established functional or pathological role[4][8]. The active counterpart, ribosomal protein L28 (RPL28), is involved in cytoplasmic protein synthesis and may show altered expression in select cancers, but RPL28P5 does not encode a functional protein and has no recognized utility as a therapeutic target, biomarker, or disease-associated gene[1][2][8].
- Other names
- RPL28_2_1625RPL28P5
02
Mechanism of action
None (no drugs act via pseudogene mechanisms; not applicable)
03
Biological functions
None (no known direct biological functions; pseudogenes typically do not encode functional proteins)
04
Disease associations
None (no direct role in diseases; parent gene RPL28 is weakly associated with colorectal cancer expression, but pseudogenes themselves are not implicated)
05
Safety considerations
None (no safety profiles or therapeutic concerns associated)
06
Interacting drugs
None (no known drugs interact with pseudogenes)
07
Biomarkers
None (not used as a biomarker in clinical/diagnostic settings)
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