Ribosomal protein L3 pseudogene 4 (RPL3P4)

Ribosomal protein L3 pseudogene 4 (RPL3P4) is a processed pseudogene in the human genome, named for its sequence similarity to the functional gene encoding ribosomal protein L3, a core component of the 60S ribosomal subunit. RPL3P4 does not code for a functional protein. It is one of multiple such processed pseudogenes dispersed throughout the genome, which arise as by-products of gene duplication and retrotransposition events and generally do not have known biological roles or direct disease associations[1][2]. RPL3P4 is not a protein-coding gene; it is a pseudogene, meaning it resembles a gene but is non-functional and does not produce a protein product[1][2]. The functional analog is Ribosomal protein L3 (*RPL3*), which is part of the ribosome, but RPL3P4 itself does not contribute to ribosome structure or function[1][2][5]. Pseudogenes are not considered druggable or therapeutic targets, nor are they established biomarkers. No drugs, mechanisms of action, disease associations, or safety considerations are listed for this pseudogene, as it lacks direct biological or therapeutic relevance in the same manner as protein-coding genes. There is nothing to suggest RPL3P4 is therapeutically actionable, has a physiologically relevant function, or plays any disease role. Instead, it is best considered a nonfunctional genomic artifact[1][2].

Other names

RPL3P4