Ribosomal protein L31 pseudogene 1 (RPL31P1)

Ribosomal protein L31 pseudogene 1 (RPL31P1) is a processed pseudogene located in the human genome that shares high sequence similarity with the functional RPL31 gene, which encodes a component of the 60S large ribosomal subunit[1][4][5]. Unlike its protein-coding counterpart, RPL31P1 is not transcribed into functional protein and lacks known biological or clinical roles. Such pseudogenes arise frequently for ribosomal protein genes due to their high expression and retrotransposition frequency[1][10]. RPL31P1 is primarily notable as a genomic artifact with no demonstrated function, disease association, or relevance as a therapeutic target. The canonical, functional gene is RPL31 (Ribosomal protein L31), which encodes a structural ribosomal protein and is involved in translation[4][7]. RPL31 is not a receptor, enzyme, or classical drug target type, but its expression may be altered in certain diseases as with many ribosomal proteins[7]. RPL31P1, as a pseudogene, does *not* encode a functional protein and does *not* participate in canonical druggable pathways[1][5]. Multiple similar pseudogenes derived from ribosomal proteins exist in the genome, none recognized as therapeutic targets[2][10]. If you need information on the *functional* ribosomal protein gene RPL31, details are available regarding its structure, function, biological role, and disease links[3][4][7]. However, RPL31P1 itself is not a molecular target by any conventional criteria.

Other names

RPL31PRPL31_35_1734RPL31P1