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RPL34P10 (Ribosomal protein L34 pseudogene 10) is a human pseudogene, identified in primary gene databases such as HGNC, NCBI Gene, and Ensembl. It is named in relation to the functional ribosomal protein L34, but unlike the parent gene, it does not code for a protein. Pseudogenes typically originate from duplication or retrotransposition events; they may retain sequence similarity to their parent gene but do not produce functional products. RPL34P10 is annotated solely as a pseudogene; it is not described as having regulatory or protein-coding capability and is not considered a direct target for therapeutic intervention, drug development, or diagnostic use[7]. While the parent gene, RPL34, encodes the ribosomal protein L34 found in the large 60S ribosomal subunit (with roles in protein synthesis and disease association such as cancer)[4], RPL34P10 is specifically categorized as a pseudogene, which distinguishes it from functional ribosomal proteins. Multiple RPL34 pseudogenes exist throughout the human genome, but only the original RPL34 gene encodes a protein with biological functions and potential disease relevance[4][7].
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