Ribosomal protein L34 pseudogene 17 (RPL34P17)

Ribosomal protein L34 pseudogene 17 (RPL34P17) is a processed pseudogene related to the ribosomal protein L34 gene (RPL34). While RPL34 encodes an essential component of the ribosome and is implicated in protein synthesis and various diseases when overexpressed, RPL34P17 does not produce a functional protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of the RPL34 gene, such as RPL34P17, dispersed throughout the human genome. These pseudogenes are generally considered non-functional and do not play a direct role in therapeutic targeting or disease mechanisms[5][4][1]. RPL34P17 appears in genomic databases as a pseudogene, not as a gene encoding a functional ribosomal protein or any protein product[5]. Functional RPL34 (not RPL34P17) is a component of the 60S ribosomal subunit and is involved in translation and protein biosynthesis[4][1]. RPL34 has been implicated in certain cancers, but this is not the case for RPL34P17, which is non-coding[4][3]. There is no evidence to support a role for RPL34P17 in therapeutic targeting, biomarker development, or drug-interaction studies. Summary: RPL34P17 is a non-functional processed pseudogene, not a molecular target, and should not be considered for therapeutic or biomarker purposes[5].

Other names

RPL34_6_902RPL34P17