Ribosomal protein L35a pseudogene (RPL35AP)

**Ribosomal protein L35a pseudogene (RPL35AP)** is a *processed pseudogene*, meaning it is a genomic sequence resembling the functional RPL35A gene but is non-functional and does not encode a protein due to lack of necessary regulatory elements or presence of disabling mutations. RPL35A pseudogenes are common, with several copies scattered across mammalian genomes, a typical feature for ribosomal protein genes[2][6]. These arise from the duplication or retrotransposition of the RPL35A gene. RPL35AP does not have a known biological function or disease association and is not considered a protein, receptor, enzyme, transporter, or therapeutic target[2][4][6]. **Clarification:** - The *pseudogene* form (RPL35AP) is distinct from the functional **RPL35A gene**, which encodes the ribosomal protein L35a needed for ribosome function and is implicated in Diamond-Blackfan anemia[1][3][5][7]. - Pseudogenes such as RPL35AP are generally non-coding and non-functional, thus are not considered drug targets, do not bind drugs, and are not implicated as biomarkers or in therapeutic safety concerns[2][4][6]. **Summary:** RPL35AP refers to a non-functional, non-coding *pseudogene* related to ribosomal protein L35a. It is not a therapeutic or biological target and has no biological, disease, or pharmacological significance[2][4][6].

Other names

bA456N23.1RPL35A_15_1710RPL35APribosomal protein L35a pseudogeneRPL35A pseudogene