Ribosomal protein L35a pseudogene 18 (RPL35AP18)

Ribosomal protein L35a pseudogene 18 (RPL35AP18) is a non-functional, processed pseudogene derived from the ribosomal protein L35a gene (RPL35A). Pseudogenes result from the duplication and subsequent mutation of a gene, rendering them non-coding and biologically inactive. RPL35AP18, like other pseudogenes, does not produce a functional protein and is not involved in ribosome structure, protein synthesis, or recognized disease pathways. Its presence in the human genome is used primarily for comparative genomics or evolutionary studies and has no established role as a therapeutic target[6]. Key points: - RPL35AP18 is a pseudogene, not a coding gene. - It does not fulfill any canonical molecular or biological function, nor is it a drug target or a known biomarker. - Queries describing RPL35AP18 as a druggable target, receptor, or functional protein are incorrect[6]. Clarification of functional counterpart: The functional gene, *ribosomal protein L35a* (RPL35A), codes for a component of the ribosomal large (60S) subunit, and mutations in this gene can be relevant to diseases like Diamond-Blackfan anemia[4][7][9], but this information does not apply to the pseudogene RPL35AP18. Summary: RPL35AP18 is **not a drug target** and **does not encode a functional molecule**; it is a processed pseudogene. Any listing of it as a therapeutic target or receptor is incorrect[6].

Other names

RPL35A_8_717RPL35AP18