ribosomal protein L35a pseudogene 27 (RPL35AP27)

Ribosomal protein L35a pseudogene 27 (RPL35AP27) is a pseudogene, which is a non-functional remnant of a gene related to the functional ribosomal protein L35a gene (RPL35A)[3][8]. Pseudogenes like RPL35AP27 do not encode a functional protein and are typically not transcribed or translated; thus, they have no direct biological function, disease role, or therapeutic relevance. RPL35AP27 is not recognized as a target for drugs, nor is it involved in signaling pathways or cellular processes as a functional protein would be. Some ribosomal protein pseudogenes have been shown to have regulatory roles or be transcribed in certain contexts, but there is no evidence that RPL35AP27 has any such function[3][8]. Additional notes: - The functional RPL35A gene (not RPL35AP27) encodes the 60S ribosomal protein L35a, a structural component of the large ribosomal subunit, and is associated with ribosome biogenesis and diseases such as Diamond-Blackfan anemia[1][7][9]. - RPL35AP27 should not be confused with RPL35A, which *is* a protein-coding gene and can have biological functions and disease associations[1][7][9]. The "pseudogene" suffix and numbering (27) indicate a non-functional copy. RPL35AP27 is *not* a therapeutic target and should not be included as one without additional functional evidence. If you are seeking information about a functional ribosomal protein, use "ribosomal protein L35a" (RPL35A)[1][7][9].

Other names

RPL35A_14_1227[3][8]