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Target intelligence / Profile preview
Ribosomal protein L35a pseudogene 35 (RPL35AP35)
- Target
- RPL35AP35
- Molecular classification
- Pseudogene, Ribosomal protein-derived pseudogene
01
Overview
RPL35AP35 (ribosomal protein L35a pseudogene 35) is a processed pseudogene located on chromosome 17q11.2. It is a non-protein-coding DNA sequence derived from the ribosomal protein L35a gene (RPL35A), which encodes a structural component of the 60S ribosomal subunit. Pseudogenes generally do not encode functional proteins, and while some can regulate parental gene expression by acting as competitive endogenous RNAs (ceRNAs) or by generating small interfering RNAs, no well-established functional or disease role has been described for RPL35AP35. It is not considered a therapeutic target, and there are no known drugs, biomarkers, or safety concerns associated with this pseudogene.
02
Mechanism of action
None — As a pseudogene, it is not a drug target
03
Biological functions
No direct, canonical function; pseudogenes may occasionally modulate parental gene expression through RNA interactions, but no well-documented biological function for RPL35AP35 specifically
04
Disease associations
No known disease association for RPL35AP35 itself; the parental RPL35A gene is implicated in Diamond-Blackfan anemia, but RPL35AP35 does not have such roles
05
Safety considerations
None documented; targeting pseudogenes is not a therapeutic strategy
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