Ribosomal protein L35a pseudogene 4 (RPL35AP4)

RPL35AP4 (Ribosomal protein L35a pseudogene 4) is a processed pseudogene in the human genome derived from the functional ribosomal protein L35a gene (RPL35A). Unlike its parent, RPL35AP4 does not encode a functional protein but may regulate gene expression through mechanisms similar to other pseudogenes, such as acting as a competitive endogenous RNA. Recent studies report that RPL35AP4 is highly expressed in glioma tissue, and its elevated levels are correlated with poorer prognosis and increased tumor malignancy. Functionally, silencing RPL35AP4 in glioma cell lines decreases proliferation, migration, and invasion capacities, and its expression is linked to immune cell infiltration in the glioma microenvironment. Therefore, RPL35AP4 may serve as a noncoding RNA biomarker for prognosis, particularly in glioma, but is not considered a standard therapeutic target. If you are seeking structured information for target/drug discovery or pharmacology, RPL35AP4 should be flagged as a non-target pseudogene biomarker candidate, not as a canonical target like a receptor or enzyme.

Other names

BPG294E21.7OTTHUMG00000140156RPL35AP4

Not applicable. No drugs target this pseudogene or its function.